Peer-reviewed Publications:

2021
  • Khan, I.; MarElia-Bennet, C.; Lefler, J.; Zuberi, M.; Denbaum, E.; Koide, A.; Connor, D.M.; Broome, A-M.; Pecot, T.; Timmers, C.; Ostrowski, M.C. Koide, S.; and O'Bryan, J.P. (2021) Targeting the KRAS alpha4-alpha5 interface inhibits pancreatic cancer tumorigenesis. Small GTPases. May 5:1-14. [PMID: 33949915] Impact factor: 9.00

2020
  • Zhang, L.; Townsend, D.M.; Morris, M.; Maldonado, E.N.; Jiang, Y-L.; Broome, A-M.; Bethard, J.R.; Ball, L.; and Tew, K.D. (2020) Voltage-dependent anion channels influence cytotoxicity of ME-344, a therpeutic isoflavone. Journal of Pharmacology and Experimental Therapeutics. 374(2): 308-318. [PMCID: PMC7372917] Impact factor: 3.87
  • Nair-Menon, J.; Daulagala, A.C.; Connor, D.M.; Rutledge, L.; Penix, T.; Bridges, M.C.; Wellslager, B.; Spyropoulos, D.D.; Timmers,C.D.; Broome, A-M.; and Kourtidis, A. (2020) Predominant distribution of RNAi machinery at apical adherens junctions in colonic epithelia is disrupted in cancer. International Journal of Molecular Science. 21(7): 2559. [PMCID: PMC7177752] Impact factor: 4.56

2019
  • Garcia, D.; Nasarre, P.; Bonilla, I.V.; Hilliard, E.; Peterson, Y.K.; Spruill, L.; Broome, A-M.; Hill, E.G.; Yustein, J.T.; Mehrotra, S.; and Klauber-Demore, N. (2019) Development of a novel huanized monoclonal antibody to secreted frizzled-related protein-2 that inhibits triple-negative breast cancer and angiosarcoma growth in vivo. Annals of Surgical Oncology. 26(13): 4782-4790. [PMID: 31515721] Impact factor: 3.86
  • Zhang, L.; Zhang, J.; Ye, Z.; Manevich, Y.; Ball, L.; Bethard, J.R.; JIang, Y-L.; Broome, A-M.; Wang, G.; Townsend, D.M.; and Tew, K.D. (2019) Heme oxygenase 1 targeting by a cytotoxic isoflavonone as a determinant of lung cancer sensitivity. Cancer Research. 79(16): 4072-4085. [PMID: PMC6697583] Impact factor: 9.13
  • Jiang, Y-L. & Broome, A-M. (2019) Novel pyrene excimer and fluorogenic probe for the detection of alkylating agents. ACS Sensors. 4(7): 1791-1797. [PMID: 31299153] Impact factor: 5.71
  • Buie, J.N; Goodwin, A.J.; Cook, J.A.; Vournakis, J.; Demcheva, M.; Zhou, Y.; Broome, A-M.; Dixit, S.; Halushka, P.V.; & Fan, H. (2019) Application of deacetylated poly-N-acetyl glucosamine nanoparticles for the delivery of miR-126 for the treatment  cecal-ligation puncture-induced sepsis. Inflammation. 42(1): 170-184. [PMID: PMC6380957] Impact factor: 3.05

2018 
  • Zhu, P.; Dixit, S.; Cheng, Q.; Tran, D.; Patel, K.; Jiang, Y-L.; Esckilsen, S.; Miller, K.; Bazzle, G.; Patterson, A.; Moore, A.; Broome, A-M. & Nadig, S. (2018) Organ preservation with targeted rapamycin nanoparticles: A pre-treatment strategy preventing chronic rejection in in vivo. RSC Advances. 8(46): 25909-25919. [PMCID: PMC6124302] Impact factor: 3.99
  • Connor, D.M. & Broome, A-M. (2018) Gold nanoparticles for the delivery of cancer therapeutics. Advances in Cancer Research. 139: 163-184. [PMID: 29941104] Impact factor: 6.27
  • Bredlau, A-L.; Motamarry, A.; Chen, C.; McCrackin, M.A.; Helke, K.; Armeson, K.E.; Bynum, K.; Broome, A-M. & Haemmerich, D. (2018) Localized delivery of therapeutic doxorubixcin dose across the canine blood-brain barrier with hyperthermia and temperature sensitive liposomes. Drug Delivery. 25(1): 973-984. [PMID: PMC6058514] Impact factor: 3.75
  • Jiang, Y-L.; Zhu, Y.; Moore, A.; Miller, K.; & Broome, A-M. (2018) Biotinylated bioluminescent probe for long lasting targeted in vivo imaging of xenografted brain tumors in mice. ACS Chemical Neuroscience. 9(1): 100-106. [PMID: PMC5947857] Impact factor: 3.88

2017
  • McKinnon, E.; Moore, A.; Dixit, S.; Zhu, Y. & Broome, A-M. (2017) Fluorescence and bioluminescence imaging of orthotopic brain tumors in mice. Methods in Molecular Biology. 1530: 283-305. [PMID: 28150209]
  • Bredlau, A-L.; Dixit, S.; Chen, C.; & Broome, A-M. (2017) Nanotechnology applications for diffuse intrinsic pontine glioma. Current Neuropharmacology. 15(1): 104-115. [PMID: PMC5327462] Impact factor: 3.75
  • Patel, K.; Broome, A-M.; Atkinson, C.; & Nadig, S. (2017) Organ preservation, ischemia reperfusion injury, and nanotherapeutics in transplantation. In: Nadig, S. & Wertheim, J. (eds): Technological Advances in Whole Organ Transplantation. NY: Springer, 14, 151-179.

2016
  • Miller, K.; Dixit, S.; Bredlau, A-L.; Moore, A.; McKinnon, E.; & Broome, A-M. (2016) Delivery of drug cache to glioma cells overexpressing platelet-derived growth factor receptor using lipid nanocarriers. Nanomedicine – Future Medicine. 11(6): 581-95. [PMID: PMC5561905] Impact factor 5.41
  • Bredlau, A-L.; McCrackin, M.A.; Montamarry, A.; Helke, K.; Chen, C.; Broome, A-M.; & Haemmerich, D. (2016) Thermal therapy approaches for treatment of brain tumors in animals and humans. Critical Reviews in Bioengineering. 44(6): 443-457. [PMID: PMC5894118] Impact factor: 2.12

2015
  • Dixit, S.; Novak, T.; Miller, K.; Zhu, Y.; Kenney, M.E.; Broome, A-M. (2015) Transferrin receptor-targeted theranostic gold nanoparticles for photosensitizer delivery in brain tumors. Nanoscale. 7(5): 1782-90. [PMID: 25519743] Impact factor: 7.39
  • Durst, R.; Peal, D. et al. (2015) Mutations in the DCHS1 gene cause mitral valve prolapse in humans. Nature. 525(7567): 109-13. [PMCID: PMC4720389] Impact factor: 29.65
  • Dixit, S.; McKinnon, E.; Miller, Zhu, Y.; K.; Novak, T.; Kenney, M.; & Broome, A-M. (2015) Dual receptor-targeted theranostic nanoparticles for localized delivery and activation of PDT drug in glioblastomas. Molecular Pharmaceutics. 12(9): 3250-60. [PMID: PMC4564323] Impact factor: 8.54
  • Broome, A-M.*; Ramamurthy, G.; Lavik, K.; Liggett, A.; Kistlinger, I.; & Basilion. J.P.* (2015) Optical imaging of targeted beta-galactosidase in brain tumors to detect EGFR levels. Bioconjugate Chemistry. 26(4): 660-8. [PMCID: PMC4437618] (*corresponding author) Impact factor: 4.82
  • Nadig, S.N.; Dixit, S.; Levey, N.; Miller, K.; Dennis, W.; Atkinson, C.; & Broome, A-M. (2015) Immunosuppressive nanotherapeutic micelles blunt endothelial cell inflammation and immunogenicity in models of transplantation. RSC Advances: 5(54): 43552-62. [PMCID: PMC4494678] Impact factor: 3.71
  • Patel, K.J.; Atkinson, C.; Broome, A-M.; McGillicuddy, J.W.; Chavin, K.D.; & Nadig, S.N. (2015) Utilization of machine perfusion and nanotechnology for liver transplantation. Current Transplantation Reports. 2(4): 303-11.
  • Meyers, J.; Chung, Y.; Broome, A-M.*; Agnes, R.S.; Wang, X.; Cheng, S.; Burda, C.*; & Basilion, J.P.* (2015) Peptide-Targeted Gold Nanoparticles for Photodynamic Therapy of Brain Cancer. Particle & Particle Systems Characterization. 32(4): 448-457. (*corresponding author) [PMID: 25999665] Impact factor: 0.81

2014
  • Perera R.H.; Solorio L.; Wu H.; Gangolli M.; Silverman E.; Hernandez C.; Peiris P.M.; Broome A-M.; & Exner A.A. (2014) Nanobubble ultrasound contrast agents for enhanced delivery of thermal sensitizer to tumors undergoing radiofrequency ablation. Pharmaceutical Research. 31(6): 1407-17. [PMCID: PMC3925199] Impact factor: 4.46
  • Shukla, S.; Wen, A.M.; Ayat, N.R.; Commandeur, U.; Gopalkrishnan, R.; Broome, A-M.; Lozada, K.; Keri, R.A.; & Steinmetz, N.F. (2014) Biodistribution and tumor-homing properties of the filamentous plant virus nanoparticle potato virus X. Nanomedicine. 9(2): 221-35. [PMID: 23834501] Impact factor: 5.06

2012
  • Agnes, R.S.; Broome, A-M.; Kavik, K.; Verma, A.; Wang, J.; & Basilion, J.P. (2012) An optical probe for noninvasive molecular imaging of orthotopic brain tumors overexpressing epidermal growth factor receptor. Molecular Cancer Therapeutics. 11(10): 2202-11. [PMCID: PMC3829608] Impact factor: 5.23

2011
  • Perera, R.H.; Krupka, T.M.; Wu, H.; Traughber, B.; Dremann, D.; Broome, A-M.; & Exner, A.A. (2011) Role of pluronic block copolymers in modulation of heat shock protein 70 expression. International Journal of Hyperthermia. 27(7): 672-81. [PMCID: PMC3294295] Impact factor: 2.71
  • Cheng, Y.; Meyers, J.D.; Agnes, R.S.; Doane, T.; Kenney, M.; Broome, A-M.*; Burda, C.*; & Basilion, J.P.* (2011) Addressing Brain Tumors with Targeted Gold Nanoparticles: A new gold standard for hydrophobic drug delivery. Small. 7(16): 2301-2306. [PMCID: PMC3837553] (*corresponding author) Impact factor: 6.17
  • Harth, K.C.; Broome, A-M., Jacobs, M.R., Blatnik, J.A.; Zeinali, F.; Bajaksouzian, S.; & Rosen M.J. (2011) Bacterial clearance of biologic grafts used in hernia repair: an experimental study. Surgical Endoscopy. 25(7): 2224-9. [PMCID: PMC3148780] Impact factor: 3.44
  • Cheng, Y.; Meyers, J.D.; Broome, A-M.*; Kenney, M.E.; Basilion, J.P.*; & Burda, C.* (2011) Deep penetration of a non-covalent PDT drug gold nanoparticle conjugate into tumors. Journal of American Chemical Society. 133(8): 2583-91 [PMCID: PMC3056176] (*corresponding author) Impact factor: 8.58

2010
  • Eckert, R.L.; Sturniolo, M.T., Broome, A-M., & Rorke, E.A. (2005) Transglutaminase function in epidermis. Journal of Investigative Dermatology 124: 481-92. [PMID: 15737187] Impact factor: 6.27
  • Broome, A-M.; Bhavsar, N.; Ramamurthy, G.; Newton, G., & Basilion, J.B. (2010) Expanding the functionality of the classic b-galactosidase complementation assay: piece by piece. Molecular Pharmaceutics 7: 60-74. Journal Cover Art. [PMCID: PMC2835542] (*corresponding author) Impact factor: 5.4
  • Halaweish, I.; Harth, K.; Broome, A-M.; Voskerician, G.; Jacobs, M.R.; & Rosen, M.J. (2010) Novel in vitro model for assessing susceptibility of synthetic hernia repair meshes to Staphylococcus aureus infection using green fluorescent protein-labeled bacteria and modern imaging techniques. Surgical Infection 11(5): 449-54. [PMCID: PMC3155689] Impact factor: 1.65
  • Sandhu, G.S.; Solorio, L.; Broome, A-M.; Salem, N.; Kolthammer, J.; Shah, T.; Flask, C.; & Duerk, J.L. (2010) Whole animal imaging. Wiley Interdisciplinary Reviews. Systems Biology and Medicine, 2(4), 398-421. [PMID: 20836038]

2005
  • Eckert, R.L.; Sturniolo, M.T.; Broome, A-M.; & Rorke, E.A. (2005) Transglutaminases in Epidermis. In: Mehta, K. and Eckert, R. (eds): Transglutaminases: Family of Enzymes with Diverse Functions. Prog Exp Tum Res. Basel: Karger, 38, 115-124. [PMID: 15746532]

2004
  • Broome, A-M. and Eckert, R.L. (2004) Microtubule-dependent redistribution of a cytoplasmic cornified envelope precursor. Journal of Investigative Dermatology 122: 29-38. [PMID: 14962086] Impact factor: 6.27
  • Editorial Commentary: Määttä, A. (2004) Roads to the edge of the cell: Intracellular transport of cornified envelope precursors. Journal of Investigative Dermatology 122: xii-xiii.
  • Eckert, R.L.; Broome, A-M.; Ruse, M.; Robinson, N.; Ryan, D.; & Lee, K. (2004) S100 proteins in the epidermis. Journal of Investigative Dermatology 123: 23-33. [PMID: 15191538] Impact factor: 6.27
  • Efimova, T.; Broome, A-M.; & Eckert, R.L. (2004) PKCd regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38d-ERK1/2 complex. Molecular Cell Biology 24: 8167-83. [PMCID: PMC515052] Impact factor: 6.19

2003
  • Broome, A-M.; Ryan, D.; & Eckert, R.L. (2003) S100 protein subcellular localization during epidermal differentiation and psoriasis. Journal of Histochemistry and Cytochemistry 51: 675-85. [PMCID: PMC3785113] Impact factor: 2.73
  • Efimova, T.; Broome, A-M.; & Eckert, R.L. (2003) A regulatory role for p38d MAPK in keratinocyte differentiation:  evidence for p38d-ERK1/2 complex formation. Journal of Biological Chemistry 278: 34277-285. [PMID: 12810719] Impact factor: 5.33
  • Ruse, M.; Broome, A-M.; & Eckert, R.L. (2003) S100A7 (psoriasin) interacts with epidermal fatty acid binding protein and localizes in focal adhesion-like structures in cultured keratinocytes. Journal of Investigative Dermatology 121: 132-41. Journal Cover Art. [PMID: 12839573] Impact factor: 6.27
  • Sturniolo, M.; Dashti, S.R.; Deucher, A.; Rorke, E.A.; Broome, A-M.; Chandraratna, R.A.S.; Keepers, T.; & Eckert, R.L. (2003) A novel tumor suppressor protein promotes keratinocyte differentiation via activation of type I transglutaminase. Journal of Biological Chemistry 278: 48066-73. [PMID: 12928434] Impact factor: 5.33

1998
  • Broome, A-M. & Millette, C.F. (1998) Sertoli cell adhesion molecules: Comparative expression of L-selectin and other CAMs in primary cells and immortalized Sertoli cell lines. Microscopy and Microanalysis 4: 1068-69. Impact factor: 3.04

1992
  • Morre, D.J.; Morre, D.M.; Paulik, M.; Batova, A.; Broome, A-M.; Pirisi, L.; & Creek, K.E. (1992) Retinoic acid and calcitiol inhibition of growth and NADH oxidase of normal and immortalized human keratinocytes. Biochim. et Biophysica Acta 1134: 217-22. [PMID: 1558845] Impact factor: 4.66
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